M. Koike, A. Kanda, K. Kido, K. Goto, Y. Kumasako, M. Nagaki, E. Otsu, Y. Araki, Y. Araki, F. Kawabe, Y. Kai, T. Utsunomiya, Effects of cyclophosphamide administration on the in vitro fertilization of mice, Reprod. Med. Biol., vol. 17, (3), 262–267, Jul. 2018.



Hatakeyama, S., Tokuoka, S., Abe, H., Araki, Y., Araki, Y. Cryopreservation of very low numbers of spermatozoa from male patients undergoing infertility treatment using agarose capsules. Human Cell, 2017, 30(3), 201–208.

Sugawara, N., Sato, R., Kato, M., Manome, T., Kimura, Y., Araki, Y., Araki, Y. Bilateral tubal pregnancies after a single-embryo transfer. Reproductive Medicine and Biology, 2017, 16(4), 396–400.

Nagatomo, H., Yao, T., Araki, Y., Mizutani, E., Wakayama, T. Agarose capsules as new tools for protecting denuded mouse oocytes/embryos during handling and freezing-thawing and supporting embryonic development in vivo. Scientific Reports, 2017, 7(1), 17960.



Araki, Y., Matsui, Y., Iizumi, A., Tsuchiya, S., Kaneko, Y., Sato, K., Ozaki, T., Araki, Y., Nishimura, M., 2016. Effect of the presence of trophectoderm vesicles on blastocyst in relation to in vitro hatching, clinical pregnancy, and miscarriage rates. Hum. Cell 29, 176–80.




Araki Y, Yao T, Asayama Y, Matsuhisa A, Araki Y. A single human sperm cryopreservation method using hollow-core agarose capsules. Fertil Steril 2015;104:1004–9.

Yokota Y, Yokota H, Yokota M, Araki Y, Araki Y. In vitro fertilization embryo development from caffeine-treated murine sperm. Reprod Med Biol 2015;14:117–21.


Hattori H, Nakamura Y, Nakajo Y, Araki Y, Kyono K. Deliveries of babies with normal health derived from oocytes with smooth endoplasmic reticulum clusters. J Assist Reprod Genet. 2014 Nov ;31(11):1461–7.

Nishimura M, Tsuchiya S, Kaneko Y, et al. Observation of a Frozen-Thawed Blastocyst Dividing via Time-Lapse Cinematography and a Possible Mechanism for a Dichorionic-Diamniotic Pregnancy. J Clin Embryol. 2014;17(2):191–195.



Sugawara, N., Maeda, M., Manome, T., Nagai, R., Araki, Y. (2013). Patients with 47, XXX karyotype who experienced premature ovarian failure (POF): two case reports. Reproductive Medicine and Biology, 12(4), 193–195.

Yokota, H., Yokota, Y., Yokota, M., Araki, Y., Araki, Y. (2013). Effect of long-term caffeine administration to mice on in vitro fertilization and embryo development using oocytes. Reproductive Medicine and Biology, 12(4), 167–171.

Nakajo, Y., Hattori, H., Sato, Y., Kanto, S., Araki, Y., Kyono, K. (2013). Vitrified-Warmed and Fresh Oocytes Yield Comparable Outcomes When Fresh Testicular Sperm Is Utilized. The Journal of Clinical Embryology, 16(2), 138-144.

Kumasako, Y., Goto, K., Koike, M., Araki, Y., Abe, H., Utsunomiya, T. (2013). Respiratory Activity of Single Blastocysts Measured by Scanning Electrochemical Microscopy: the Relationship between Pre-freezing and Post-warming. Journal of Mammalian Ova Research Vol. 30(2013) No. 1, 30(1), 30-35.

Sugawara, N., Kimura, Y., & Araki, Y. (2013). Case report: a successful pregnancy outcome in a patient with non-mosaic Turner syndrome (45, X) via in vitro fertilization. Human cell, 26(1), 41-43.


Sugawara, N., Kimura, Y., & Araki, Y. (2012). A successful second delivery outcome using refrozen thawed testicular sperm from an infertile male true hermaphrodite with a 46, XX/46, XY karyotype: case report. Human cell, 25(4), 96-99.

Hiroshi Kamiyama, Taketoshi Shimizu, Tomomi Oki, Terumi Asada, Yasuyuki Araki, Yasuhisa Araki, Successful delivery following intracytoplasmic sperm injection with calcium ionophore A23187 oocyte activation in a partially globozoospermic patient. Reproductive Medicine and Biology (2012) Volume 11, Issue 3, pp 159-164.

Hiroshi, K., Taketoshi, S., Tomomi, O., Terumi, A., Yasuhisa, A. (2012). Successful Management of Infertility due to Complete Retrograde Ejaculation via Intracytoplasmic Sperm Injection using Bladder Washing Sperm and Testicular Extract Sperm: A Report of Two Cases. The. Journal. of. Clinical. Embryology, 14(4), 8-11.


Murakami M, Egashira A, Murakami K, Araki Y, Kuramoto T: Perinatal outcome of twice-frozen-thawed embryo transfers: a clinical follow-up study. Fertil Steril (2011) 95:2648-2650


Gohbara A, Katagiri K, Sato T, Kubota Y, Kagechika H, Araki Y, Araki Y, Ogawa T: In Vitro Murine Spermatogenesis in an Organ Culture System. Biol Reprod. 2010 Apr (2010) :14

Araki Y, Sato T, Katagiri K, Kubota Y, Araki Y, Ogawa T: Proliferation of mouse spermatogonial stem cells in microdrop culture. Biol Reprod (2010) 83:951-957

Nobuo Sugawara, Hideyuki Fukuchi, Machiko Maeda, Rie Komaba, Yasuhisa Araki.: Sex-discordant twins despite single embryo transfer: a report of two cases. Reprod Med Biol (2010) 9:169-172


Kyono K, Nakajo Y, Doshida M, Toya M, Araki Y: Birth of a healthy male infant after transfer of vitrified-warmed blastocysts derived from intracytoplasmic sperm injection with vitrified-warmed oocytes and frozen-thawed spermatozoa. J Assist Reprod Genet. (2009) 26:451-453

Kyono K, Nakajo Y, Nishinaka C, Araki Y, Doshida M, Toya M, Kanto S: A birth of twins-one boy and one girl-from a single embryo transfer and a possible natural pregnancy. J Assist Reprod Genet (2009) 26:553-554

Kumasako Y, Otsu E, Utsunomiya T, Araki Y: The efficacy of the transfer of twice frozen-thawed embryos with the vitrification method. Fertil Steril vol.91, (2009) No.2:383-386


Kyono K, Kumagai S, Nishinaka C, Nakajo Y, Uto H, Toya M, Sugawara J, Araki Y: Birth and follow-up of babies born following ICSI using SrCl2 oocyte activation. Reprod Biomed Online (2008) 17:53-58

Kyono K, Nakajo Y, Nishinaka C, Hattori H, Kyoya T, Ishikawa T, Abe H, Araki Y: A birth from the transfer of a single vitrified-warmed blastocyst using intracytoplasmic sperm injection with calcium ionophore oocyte activation in a globozoospermic patient. Fertil Steril. Vol.91, (2008) No.3:931.e7-931.e11


H. Abe, M. Yokoo, T. Itoh-Sasaki, M. Nasu, K. Goto, Y. Kumasako, Y. Araki, H. Shiku, T. Matsue and T. Utsunomiya: Estimation of Respiratory Activity of Individual Human Embryos by Scanning Electrochemical Microscopy 14th World congress on In vitro fertirization & 3rd World congress on In vitro (2007) :

Kyono K, Uto H, Nakajo Y, Kumagai S, Araki Y, Kanto S: Seven pregnancies and deliveries from non-mosaic Klinefelter syndrome patients using fresh and frozen testicular sperm. J Assist Reprod Genet (2007) 24:47-51


Araki Yasuyuki, Yoshizawa Midori, Araki Yasuhisa: Visualization of human sperm chromosomes by using mouse oocytes cryothawed after enucleation. Fertil Steril (2006) 86:348-351


Sugawara, Nobuo, Tokunaga, Yo, Maeda, Machiko, Komaba, Rie, Araki, Yasuhisa: A successful pregnancy outcome using frozen testicular sperm from a chimeric infertile male with a 46, XX/46, XY karyotype: case report. Hum Reprod (2005) 20:147-148

Sato S, Yokota Y, Yokota H, Yokota M, Araki Y: A Novel Method for Mechanically-Assisted Hatching Using a Razor on Human Blastocyst Embryos ASRM2005 (2005) :

Yokota Y, Sato S, Ishikawa Y, Makita K, Asada T, Araki Y: Fertilization and Pregnancy Rate Increased Following Chemical Activation (Ca Ionophore) of Oocytes in Patients Who Repeated Fertilization Failure Using Intracytoplasmic Sperm Injection ASRM2005 (2005) :

Y. Araki, M. Yoshizawa, Y. Araki: Use of enucleated mouse oocytes to analyze metaphase chromosomes derived from human sperm ESHRE2005 (2005) :

Kumasako, Yoko, Kumon, Mami, Utsunomiya, Takafumi, Araki, Yasuhisa: Successful pregnancy after the vitrification of zygotes using commercial vitrification solutions and conventional straws to protect against infections in liquid nitrogen. J Assist Reprod Genet (2005) 22:33-35

Araki, Yasuyuki, Yoshizawa, Midori, Araki, Yasuhisa: A novel method for chromosome analysis of human sperm using enucleated mouse oocytes. Hum Reprod (2005) 20:1244-1247

R. Komaba, N. Sugawara, M. Maeda, N. Fujii, Y. Araki: Successful pregnancy from abnormal X-chromosome karyotypes including mosaic 45,X after repeated failure of assisted reproductive technology ESHRE2005 (2005) :

M. Maeda, N. Sugawara, R. Komaba, N. Fujii, Y. Araki: First polar body morphology before ICSI is related to embryo quality and fragmentation ESHRE2005 (2005) :


Araki, Yasuyuki, Yoshizawa, Midori, Abe, Hiroyuki, Murase, Yoshihiko, Araki, Yasuhisa: Use of mouse oocytes to evaluate the ability of human sperm to activate oocytes after failure of activation by intracytoplasmic sperm injection. Zygote (2004) 12:111-116

Murase, Yoshihiko, Araki, Yasuyuki, Mizuno, Satoshi, Kawaguchi, Choji, Naito, Mayumi, Yoshizawa, Midori, Araki, Yasuhisa: Pregnancy following chemical activation of oocytes in a couple with repeated failure of fertilization using ICSI: case report. Hum Reprod (2004) 19:1604-1607

Nakajo, Yukiko, Fukunaga, Noritaka, Fuchinoue, Kohei, Yagi, Akiko, Chiba, Setsuyo, Takeda, Miho, Kyono, Koichi, Araki,Yasuhisa: Physical and mental development of children after in vitro fertilization and embryo transfer Reproductive Medicine and Biology (2004) 3:63-67

Yasuyuki Araki, Midori Yoshizawa, Yasuhisa Araki: Use of enucleated mouse oocytes to analyze metaphase chromosomes derived from human sperms The 4rd conference of the pacific rim society for fertility and (2004) :

Yoshida, Hiroaki, Oomiya, Yuki, Sato, Tomoko, Aono, Nobuya, Araki, Yasuhisa: A successful pregnancy and delivery outcome for a 46-year-old woman following in vitro fertilization Reproductive Medicine and Biology (2004) 3:39-42

Y.Yokota, M. Makita, M. Yokota, H. Yokota, S. Sato, Y. Araki: Follicular fluid testosterone level and pregnancy rate in relation to caffeine intake ESHRE2004 (2004) :

Otsu, Eiko, Sato, Akiko, Nagaki, Miyuki, Araki, Yasuhisa, Utsunomiya, Takafumi: Developmental potential and chromosomal constitution of embryos derived from larger single pronuclei of human zygotes used in in vitro fertilization. Fertil Steril (2004) 81:723-724

Sasaki, Sachiko, Sasaki, Keiko, Takahashi, Sayaka, Sasaki, Toshie, Kyono, Koichi, Araki, Yasuhisa: Successful pregnancy outcome using sperm from severely diseased men with testicular cancer and collagen disease: Three case reports Reproductive Medicine and Biology (2004) 3:69-75

Takahashi, Tomomi, Araki, Yasuhisa: Successfully Healthy Baby Delivery from Human Refrozen Blastocyst Embryos by Vitrification J Mamm Ova Res (2004) 21:162-165


Kyono ,Koichi, Fukunaga, Noritaka, Chiba, Setsuyo, Nakajo, Yukiko, Fuchinoue, Kohei, Yagi, Akiko, Araki, Yasuhisa: Two-step consecutive transfer of early embryos and blastocysts Reproductive Medicine and Biology (2003) 2:133-137

Kumon, Mami, Kumasako, Yoko, Utsunomiya, Takafumi, Araki, Yasuhisa: A Vitrification Method by Means of a Straw to Prevent Infections in Mouse Pronuclear Embryos J Mamm Ova Res (2003) 20:124-128

Yokota, Yoshimasa, Yokota, Mikako, Yokota, Hidemi, Makita, Masami, Sato, Setsuko, Araki, Yasuhisa: Enhancing the fertility of poor responders by treatment with estrogen rebound combined with a short protocol Reproductive Medicine and Biology (2003) 2:127-131

Yoshida, Hiroaki, Aono, Nobuya, Araki,Yasuhisa, Naganuma, Takako: Delivery of a healthy newborn using vitrified zygotes that developed from in vitro matured oocytes retrieved from a patient with polycystic ovarian syndrome Reproductive Medicine and Biology (2003) 2:87-90

Yokota, Yoshimasa, Yokota, Mikako, Yokota, Hidemi, Ishikawa, Yasuko, Sato, Setsuko, Araki, Yasuhisa: Relationship between follicular fluid hormone levels, embryo quality, and maternal age during in vitro fertilization after the short or long protocol with a gonadotropin releasing hormone agonist Reproductive Medicine and Biology (2003) 2:165-169


Kyono, Koichi, Fukunaga, Noritaka, Haigo, Kosuke, Chiba, Setsuyo, Ohira, Chisako, Nakajo, Yukiko, Araki, Yasuhisa: Successful delivery following cryopreservation of zygotes produced by in vitro matured oocytes retrieved from a woman with polycystic ovarian syndrome-like disease: a case report. J Assist Reprod Genet (2002) 19:390-393

Kyono,K, Fukunaga,N, Haigo, K, Chiba, S, Ohira, C, Nakajo, Y, Araki, Y: Paternal 45, X/ 46, X, r(Y) Karyotype Which has Both SRY and DAZ Gene Transmitted to Twin Fetus after Intracytoplasmic Sperm Injection for Oligozoospermia: A Case report Jpn J Fertil Steril (2002) 47:87-91

Araki Y, Yoshizawa M, Abe H, Murase Y and Araki Y: Evaluation of a Human Sperm Injected into Mouse Oocytes Using Sperm, which Failed to Fertilize by Intracytoplasmic Sperm Injection The 3rd conference of the pacific rim society for fertility and (2002) :



Fukunaga, N, Haigo, K, Kyono, K, Araki, Y: Efficiency of using frozen-thawed testicular sperm for multiple intracytoplasmic sperm injections. J Assist Reprod Genet (2001) 18:634-637

Yokota, Y, Yokota, H, Yokota, M, Sato, S, Araki, Y: Birth of healthy twins from in vitro development of human refrozen embryos. Fertil Steril (2001) 76:1063-1065

Yokota, Y, Sato, S, Yokota, M, Yokota, H, Araki, Y: Birth of a healthy baby following vitrification of human blastocysts. Fertil Steril (2001) 75:1027-1029

Kyono, K, Fukunaga, N, Haigo, K, Chiba, S, Araki, Y: Pregnancy achieved following ICSI from a man with Klinefelter's syndrome and spinal cord injury. Hum Reprod (2001) 16:2347-2349


Yokota, Y, Sato, S, Yokota, M, Ishikawa, Y, Makita, M, Asada, T, Araki, Y: Successful pregnancy following blastocyst vitrification: case report. Hum Reprod (2000) 15:1802-1803

Ogawa, S, Araki, S, Araki, Y, Ohno, M, Sato, I: Chromosome analysis of human spermatozoa from an oligoasthenozoospermic carrier for a 13;14 Robertsonian translocation by their injection into mouse oocytes. Hum Reprod (2000) 15:1136-1139

Araki, Yasuhisa, Ohno, Michiko, Motoyama, Mitshhiro, Araki, Sigeo: Birth of a Healthy Baby Following the Intracytoplasmic Injection of Ejaculated Spermatozoa from a Non-Mosaic XYY Patient Jpn J Fertil Steril (2000) 45:279-283


Araki, Y, Ogawa, S, Ohno, M, Yoshizawa, M, Motoyama, M, Araki, S, Aslam, I, Fishel, S: Successful metaphase chromosome analysis of human elongated spermatids using mouse oocytes. Mol Hum Reprod (1999) 5:784-787

Takahashi, K, Araki, Y, Motoyama, M: Normal development of a zona-free oocyte to the blastocyst stage following ICSI. Hum Reprod (1999) 14:2677


Araki, Y, Motoyama, M, Yoshida, A, Kamiyama, H, Araki, S: In-situ hybridization chromosome analysis of XYY and XXY males' spermatozoa. Hum Reprod (1997) 12:1604

Araki, Y, Motoyama, M, Yoshida, A, Kim, S Y, Sung, H, Araki, S: Intracytoplasmic injection with late spermatids: a successful procedure in achieving childbirth for couples in which the male partner suffers from azoospermia due to deficient spermatogenesis. Fertil Steril (1997) 67:559-561

Yoshida, A, Araki, Y, Motoyama, M, Kim, S Y, Sung, H, Araki, S, Miura, K, Shirai, M: Structural abnormalities of autosomal chromosomes in the male partner do not influence fertilization and early development of embryos after intracytoplasmic sperm injection. Hum Reprod (1997) 12:2499-2503

Yoshizawa, M, Konno,H, Zhu, S, Kageyama,S, Fukui, E, Muramatsu, S, Kim, S, Araki, Y: Chromosomal diagnosis in each individual blasomere of 5- to 10-cell bovine embryos derived from in vitro fertilization 3rd Asian simposium on animal biotechnology (1997) 12:

Yoshizawa, Y, Araki, Y, Motoyama,M: Analyses of early deveropment and chromosomal constitution of tripronuclear human and mouse eggs fertilized in vitro Jpn J Fertil Steril (1997) 42:35-38

Sung, H, Araki, Y, Motoyama, M, Kim, SK, Yoshida, A, Araki, S: Assessment of human sperm using the acrosin index to provide a relative measure of various enhancing / inhibitory sperm factors involved in fertilization Arch Androl (1997) 13:291-306

Yoshida, A, Miura, K, Shirai, M, Motoyama, M, Araki, Y, Araki, S: Bromocriptine treatment outcome for a pituitary adenoma patient suffering from male infertility Jpn J Fertil Steril (1997) 42:324-327

Yoshida, A, Nakahori, Y, Kuroki, Y, Motoyama, M, Araki, Y, Miura, K, Shirai, M: Dicentric Y chromosome in an azoospermic male. Mol Hum Reprod (1997) 3:709-712